Plastomet (50 mg) Injection Side Effects and usage

Plastomet (50 mg) - Methotrexate- Injection is manufactured by Khandelwal Laboratories Pvt Ltd. and the main constituent generic drug is Methotrexate- 25 mg.

Side Effects

Megaloblastic anaemia, pancytopenia, desquamation and bleeding may occur in GIT.
Skin reactions, alopecia, ocular irritation, arachnoiditis in intrathecal use, megaloblastic anaemia, osteoporosis, precipitation of diabetes, arthralgias.
Interstitial lung disease, leukoencephalopathy.


Maintaining remission in children with acute leukaemias.
Autoimmune diseases like rapidly progressing rheumatoid arthritis, severe psoriasis, pemphigus, myasthenia gravis, uveitis, chronic active hepatitis.

Contra Indications

Pregnancy and lactation.
Severe renal or hepatic impairment, pre-existing profound bone-marrow suppression.


Early hepatic and renal dysfunction.
CNS disturbances.
Bone marrow depression, elderly, neonates.
Use of folinic acid rescue has permitted much higher doses of methotrexate.


The cost of the drug per 1 ml is Rs.30 in India as of date.


Plastomet (50 mg) Injection mainly contains the generic formulation called as Methotrexate- 25 mg.

Plastomet (50 mg) Injection Medicine Details

Medicine Name: Plastomet (50 mg) Injection
Manufacturer: Khandelwal Laboratories Pvt Ltd.
Generic Molecule: Methotrexate

Plastomet (50 mg) Injection Similar Medicines List:

Plastules B12 Capsule
Plastules Folic 16 Mg 0 75 Mg 7 5 Mcg Capsule
Platfree 75 Mg Tablet
Platfrin 150 Mg Tablet
Platfrin 75 Mg Tablet

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