Plastomet (50 mg) Injection Side Effects and usage

What are the Plastomet (50 mg) Injection medicine side effects read here and discuss in Plastomet (50 mg) Injection Forum.

Read about what are the Plastomet (50 mg) Injection medicine side effects, how and when to use Plastomet (50 mg) Injection, common indications of Plastomet (50 mg) Injection, when not to use Plastomet (50 mg) Injection (contra indications), manufacturer, price and generic molecules.

Plastomet (50 mg) - Methotrexate- Injection is manufactured by Khandelwal Laboratories Pvt Ltd. and the main constituent generic drug is Methotrexate- 25 mg.

Plastomet (50 mg) Injection Medicine Side effects and usage

Side Effects

Megaloblastic anaemia, pancytopenia, desquamation and bleeding may occur in GIT.
Skin reactions, alopecia, ocular irritation, arachnoiditis in intrathecal use, megaloblastic anaemia, osteoporosis, precipitation of diabetes, arthralgias.
Interstitial lung disease, leukoencephalopathy.

Indications

Maintaining remission in children with acute leukaemias.
Autoimmune diseases like rapidly progressing rheumatoid arthritis, severe psoriasis, pemphigus, myasthenia gravis, uveitis, chronic active hepatitis.

Contra Indications

Pregnancy and lactation.
Severe renal or hepatic impairment, pre-existing profound bone-marrow suppression.
AIDS.

Caution

Early hepatic and renal dysfunction.
CNS disturbances.
Bone marrow depression, elderly, neonates.
Use of folinic acid rescue has permitted much higher doses of methotrexate.

Cost

The cost of the drug per 1 ml is Rs.30 in India as of date.

Formulation

Plastomet (50 mg) Injection mainly contains the generic formulation called as Methotrexate- 25 mg.

Plastomet (50 mg) Injection Medicine Generics

Medicine Name: Plastomet (50 mg) Injection
Manufacturer: Khandelwal Laboratories Pvt Ltd.
Generic Molecule: Methotrexate

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